Monastrol

目录号: A11976

Kinesin-5(KIF11) 抑制剂

Monastrol

Monastrol Chemical Structure

CAS NO. 329689-23-8

Monastrol是一种有效的,细胞可渗透的非微管蛋白相互作用的有丝分裂抑制剂。Monastrol通过与有丝分裂驱动蛋白Eg5结合来阻断有丝分裂(IC50 = 14μM),Eg5是纺锤体双极性所必需的运动蛋白。

库存: 现货

规格 价格 数量
5 mg
¥ 800.00
10 mg
¥ 1,100.00
25 mg
¥ 2,300.00
50 mg
¥ 3,900.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Monastrol是一种有效的,细胞可渗透的非微管蛋白相互作用的有丝分裂抑制剂。Monastrol通过与有丝分裂驱动蛋白Eg5结合来阻断有丝分裂(IC50 = 14μM),Eg5是纺锤体双极性所必需的运动蛋白。
In vitro DMSO 54 mg/mL (184.71 mM)
Water Insoluble
Ethanol 54 mg/mL (184.71 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.2 mL 171 mL 342 mL
0.5 mM 6.84 mL 34.2 mL 68.4 mL
1 mM 3.42 mL 17.1 mL 34.2 mL
5 mM 0.68 mL 3.42 mL 6.84 mL

*The above data is based on the productmolecular weight 292.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11976
作用机制 Inhibitor (抑制剂)
M. Wt 292.4
Formula C14H16N2O3S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 329689-23-8
SMILES CCOC(=O)C1=C(NC(=S)NC1C2=CC(=CC=C2)O)C

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