Monomethyl auristatin E

目录号: A12954

Monomethyl auristatin E

Monomethyl auristatin E Chemical Structure

CAS NO. 474645-27-7

Monomethyl auristatin E (MMAE) is an antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin, and also shows inhibition of antibody-drug conjugates (ADCs) activity.

库存: 现货

规格 价格 数量
5 mg
¥ 1,200.00
10 mg
¥ 1,800.00
25 mg
¥ 2,800.00
50 mg
¥ 4,800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Monomethyl auristatin E (MMAE) is an antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin, and also shows inhibition of antibody-drug conjugates (ADCs) activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.93 mL 69.64 mL 139.28 mL
0.5 mM 2.79 mL 13.93 mL 27.86 mL
1 mM 1.39 mL 6.96 mL 13.93 mL
5 mM 0.28 mL 1.39 mL 2.79 mL

*The above data is based on the productmolecular weight 717.98. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12954
MECHANISM OF ACTION Stimulator
M. Wt 717.98
Formula C39H67N5O7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 474645-27-7
Synonyms Monomethylauristatin E, MMAE
SMILES CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@H](C)[C@H](C2=CC=CC=C2)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC

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