微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
Motesanib(AMG706)是一种多激酶抑制剂，可选择性靶向VEGF受体，血小板衍生的生长因子受体（PDGFRs）和Kit受体，并带有IC50受体。值分别为2 nM（VEGFR1），3 nM（VEGFR2），6 nM（VEGFR3），84 nM（PDGFR）和8 nM（Kit）。
| In vitro | DMSO | 68 mg/mL (182.09 mM) | |
| Water | Insoluble | ||
| Ethanol | 7 mg/mL (18.74 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.78 mL | 133.89 mL | 267.77 mL |
| 0.5 mM | 5.36 mL | 26.78 mL | 53.55 mL |
| 1 mM | 2.68 mL | 13.39 mL | 26.78 mL |
| 5 mM | 0.54 mL | 2.68 mL | 5.36 mL |
*The above data is based on the productmolecular weight 373.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11496 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 373.45 |
| Formula | C22H23N5O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 453562-69-1 |
| Synonyms | AMG 706, AMG-706 |
| SMILES | CC1(CNC2=C1C=CC(=C2)NC(=O)C3=C(N=CC=C3)NCC4=CC=NC=C4)C |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
XL647 (Tesevatinib)
XL647 (Tesevatinib)是一种口服生物可利用的小分子RTK抑制剂，可结合并抑制在肿瘤细胞增殖和肿瘤血管形成中…
ZM 306416
ZM 306416 hydrochloride是一种VEGF受体酪氨酸激酶抑制剂，可抑制KDR（IC50 = 100 nM）和Flt（IC50 = 2 uM）酪氨酸激酶…
Cediranib (AZD2171)
Cediranib (AZD2171)是一种高效的VEGFR(KDR)抑制剂，此外对c-Kit和PDGFRβ也具有相似的抑制活性，对VEGFR的选择性比P…
Kaempferol
Kaempferol被发现抑制Ki为0.3-0.5 μM的牛主动脉肌球蛋白轻链激酶，并且还被发现通过新的ERK-NFκB-cMyc-p21途径抑…
Buflomedil HCl
Buflomedil HCl是一种用于治疗外周血管疾病的血管活性剂。
BMS-817378
BMS-817378是Met/VEGFR-2双重抑制剂BMS-794833的新型前药。
Keywords:购买 Motesanib (AMG706) | Motesanib (AMG706) 供应商 | 订购 Motesanib (AMG706) | Motesanib (AMG706) 价格 | Motesanib (AMG706) 生产商 | 订单 Motesanib (AMG706) | Motesanib (AMG706) 代理商 | 购买 453562-69-1| 453562-69-1 供应商 | 订购 453562-69-1 | 453562-69-1 价格 | 453562-69-1 生产商 | 订单 453562-69-1 | 453562-69-1 代理商|buy Motesanib (AMG706) | Motesanib (AMG706) Supplier | purchase Motesanib (AMG706) | Motesanib (AMG706) cost | Motesanib (AMG706) manufacturer | order Motesanib (AMG706) | Motesanib (AMG706) distributor | buy 453562-69-1| 453562-69-1 Supplier | purchase 453562-69-1 | 453562-69-1 cost | 453562-69-1 manufacturer | order 453562-69-1 | 453562-69-1 distributor