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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Moxifloxacin HCl 发表的文献 (2)
- Hiroshi Arakawa, .et al. Possible interaction of quinolone antibiotics with peptide transporter 1 in oral absorption of peptide-mimetic drugs, Biopharm Drug Dispos, 2016, Jan;37(1):39-45 PMID: 26590007
- Arisa Higa, .et al. Differing responses of human stem cell-derived cardiomyocytes to arrhythmogenic drugs, determined using impedance measurements, Fundam. Toxicol. Sci, 2016, 3(2): 47-53
Chemical Information
| 目录号 | A10609 |
|---|---|
| Mechanism of action | Inhibitor |
| 分子量 | 437.9 |
| 化学分子式 | C21H24FN3O4.HCl |
| Solubility | DMSO |
| 纯度 | >98% |
| 储存方式 | at -20°C 2 years |
| CAS No. | 186826-86-8 |
| Synonyms | Avelox, Avalox, BAY 12-8039 |
| SMILES code | COC1=C2C(=CC(=C1N3C[C@@H]4CCCN[C@@H]4C3)F)C(=O)C(=CN2C5CC5)C(=O)O.Cl |
| 化学名称 | (1's,6's)-1-cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride |
Description |
Moxifloxacin is a quinolone/fluoroquinolone antibiotic. | ||||||||||
Targets |
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| Solubility (25°C) * | In vitro | DMSO | 88 mg/mL (200.96 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
| In vivo | 30% PEG400/0.5% Tween80/5% propylene glycol | 30 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.84 mL | 114.18 mL | 228.36mL |
| 0.5 mM | 4.57 mL | 22.84 mL | 45.67 mL |
| 1 mM | 2.28 mL | 11.42 mL | 22.84 mL |
| 5 mM | 0.46 mL | 2.28 mL | 4.57 mL |
*The above data is based on the productmolecular weight 437.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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