MPEP

目录号: A12589

mGlu5 receptor 拮抗剂

MPEP

MPEP Chemical Structure

CAS NO. 96206-92-7

MPEP是mGlu5受体亚型(IC50 = 36 nM)的有效且高度选择性的非竞争性拮抗剂,并且是mGlu4受体的正构构调节剂。

库存: 现货

规格 价格 数量
10 mg
¥ 500.00
25 mg
¥ 1,000.00
50 mg
¥ 1,600.00
100 mg
¥ 2,800.00
10mM * 1mL in DMSO
¥ 700.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

MPEP是mGlu5受体亚型(IC50 = 36 nM)的有效且高度选择性的非竞争性拮抗剂,并且是mGlu4受体的正构构调节剂。
靶点信息
mGluR5
36 nM
In vitro (25°C) DMSO 36 mg/mL (186.3 mM)
Water Insoluble
Ethanol 36 mg/mL (186.3 mM)
In vivo 2% DMSO+30% PEG 300+5% Tween 80 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 51.75 mL 258.73 mL 517.47 mL
0.5 mM 10.35 mL 51.75 mL 103.49 mL
1 mM 5.17 mL 25.87 mL 51.75 mL
5 mM 1.03 mL 5.17 mL 10.35 mL

*The above data is based on the productmolecular weight 193.249. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12589
作用机制 Antagonist (拮抗剂)
M. Wt 193.249
Formula C14H11N
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 96206-92-7
SMILES CC1=CC=CC(=N1)C#CC2=CC=CC=C2

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