MRK 560

目录号: A15304

γ-secretase inhibitor

MRK 560 Chemical Structure

CAS NO. 677772-84-8

MRK 560 is an orally bioavailable gamma-secretase inhibitor with the ability to markedly reduce Abeta peptide in the brain and CSF of the rat and confirm the utility of the rat for assessing the effects of gamma-secretase inhibitors on central nervous system Abeta(40) levels in vivo.

库存: 现货

规格 价格 数量
10 mg
¥ 1,700.00
50 mg
¥ 7,600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

MRK 560 is an orally bioavailable gamma-secretase inhibitor with the ability to markedly reduce Abeta peptide in the brain and CSF of the rat and confirm the utility of the rat for assessing the effects of gamma-secretase inhibitors on central nervous system Abeta(40) levels in vivo.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.31 mL 96.54 mL 193.08 mL
0.5 mM 3.86 mL 19.31 mL 38.62 mL
1 mM 1.93 mL 9.65 mL 19.31 mL
5 mM 0.39 mL 1.93 mL 3.86 mL

*The above data is based on the productmolecular weight 517.92. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15304
MECHANISM OF ACTION Inhibitor
M. Wt 517.92
Formula C19H17ClF5NO4S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 677772-84-8
Synonyms MRK-560, MRK560
SMILES C1CC(CCC1NS(=O)(=O)C(F)(F)F)(C2=C(C=CC(=C2)F)F)S(=O)(=O)C3=CC=C(C=C3)Cl

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