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MRK 560是一种可用的γ-分泌酶抑制剂，能够显着减少大鼠脑和CSF中的Abeta肽，并证实该大鼠可用于评估γ-分泌酶抑制剂对中枢神经系统Abeta的作用（40）体内水平。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.31 mL | 96.54 mL | 193.08 mL |
| 0.5 mM | 3.86 mL | 19.31 mL | 38.62 mL |
| 1 mM | 1.93 mL | 9.65 mL | 19.31 mL |
| 5 mM | 0.39 mL | 1.93 mL | 3.86 mL |
*The above data is based on the productmolecular weight 517.92. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15304 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 517.92 |
| Formula | C19H17ClF5NO4S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 677772-84-8 |
| Synonyms | MRK-560, MRK560 |
| SMILES | C1CC(CCC1NS(=O)(=O)C(F)(F)F)(C2=C(C=CC(=C2)F)F)S(=O)(=O)C3=CC=C(C=C3)Cl |
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