MRT67307
目录号: A11485
SIK/TBK-1/IKKe 抑制剂
MRT67307 是一种强效的双重 IKKε 和 TBK1 抑制剂，其 IC50 分别为 160 和 19 nM。
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生物活性
| Discription | MRT67307 is a potent and dual IKKε and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively. | ||
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| Targets |
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产品信息
| 目录号 | A11485 |
|---|---|
| 分子式 | C26H36N6O2 |
| 分子量 | 464.6 |
| CAS号 | 1190378-57-4 |
| SMILES | C1CC(C1)C(=O)NCCCNC2=NC(=NC=C2C3CC3)NC4=CC=CC(=C4)CN5CCOCC5 |
| 其他名称 | MRT 67307, MRT-67307 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | Warmed: 87 mg/mL | |
| Water | 87 mg/mL | ||
| Ethanol | 87 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.52 mL | 107.62 mL | 215.24 mL |
| 0.5 mM | 4.3 mL | 21.52 mL | 43.05 mL |
| 1 mM | 2.15 mL | 10.76 mL | 21.52 mL |
| 5 mM | 0.43 mL | 2.15 mL | 4.3 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1190378-57-4 | 1190378-57-4 供应商 | 1190378-57-4 花费 | 1190378-57-4 生产商 | 订购 1190378-57-4 | 1190378-57-4 代理商