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SIK/TBK-1/IKKe 抑制剂

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产品目录号: A11485


产品名 目录号 价格 数量
MRT67307 10mg A11485-10
¥ 1,300.00
MRT67307 25mg A11485-25
¥ 2,800.00
MRT67307 50mg A11485-50
¥ 3,500.00



MRT67307 is a potent and dual IKKϵ and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively.





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Chemical Information

目录号 A11485
Mechanism of action Inhibitor
分子量 464.6
化学分子式 C26H36N6O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1190378-57-4
Synonyms MRT 67307, MRT-67307
化学名称 N-[3-[[5-cyclopropyl-2-[3-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide hydrochloride


MRT67307 is a potent and dual IKKϵ and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.52 mL 107.62 mL 215.24mL
0.5 mM 4.3 mL 21.52 mL 43.05 mL
1 mM 2.15 mL 10.76 mL 21.52 mL
5 mM 0.43 mL 2.15 mL 4.3 mL

*The above data is based on the productmolecular weight 464.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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