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MRT68921

Autophagy ULK1/2 抑制剂

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产品目录号: A15880

库存状态:中国现货中国现货

产品名 目录号 价格 数量
MRT68921 10mg A15880-10
¥ 1,200.00
MRT68921 25mg A15880-25
¥ 2,500.00
MRT68921 50mg A15880-50
¥ 4,200.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.

MRT68921

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Chemical Information

目录号 A15880
Mechanism of action Inhibitor
分子量 434.58
化学分子式 C25H34N6O??xHCl
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1190379-70-4
Synonyms MRT67307 HCl
SMILES code O=C(C1CCC1)NCCCNC2=CC(NC3=CC4=C(CN(C)CC4)C=C3)=CC=C2C5CC5.[H]Cl.[H]Cl
化学名称 N-[3-[[5-cyclopropyl-2-[(1,2,3,4-tetrahydro-2-methyl-6-isoquinolinyl)amino]-4-pyrimidinyl]amino]propyl]-Cyclobutanecarboxamide hydrochloride

生物活性

Description
MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.01 mL 115.05 mL 230.11mL
0.5 mM 4.6 mL 23.01 mL 46.02 mL
1 mM 2.3 mL 11.51 mL 23.01 mL
5 mM 0.46 mL 2.3 mL 4.6 mL

*The above data is based on the productmolecular weight 434.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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