MS-275 (Entinostat)

目录号: A10611

HDAC 抑制剂

MS-275 (Entinostat)

MS-275 (Entinostat) Chemical Structure

CAS NO. 209783-80-2

MS-275 (Entinostat)是一种有效的HDAC抑制剂,对HDAC1和HDAC3的IC50分别为0.3和8uM。

库存: 现货

规格 价格 数量
10 mg
¥ 400.00
25 mg
¥ 700.00
50 mg
¥ 900.00
200 mg
¥ 1,900.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

MS-275 (Entinostat)是一种有效的HDAC抑制剂,对HDAC1和HDAC3的IC50分别为0.3和8uM。
靶点信息
HDAC1 (Cell-free assay) HDAC3 (Cell-free assay)
0.51 μM1.7 μM
In vitro (25°C) DMSO 75 mg/mL (199.25 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.57 mL 132.84 mL 265.67 mL
0.5 mM 5.31 mL 26.57 mL 53.13 mL
1 mM 2.66 mL 13.28 mL 26.57 mL
5 mM 0.53 mL 2.66 mL 5.31 mL

*The above data is based on the productmolecular weight 376.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10611
作用机制 Inhibitor (抑制剂)
M. Wt 376.4
Formula C21H20N4O3
Solubility DMSO>75mg/mL Water<1mg/mL Ethanol<1mg/mL
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 209783-80-2
Synonyms SNDX-275
SMILES C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3

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