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MS023

促销

PRMT1 抑制剂

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产品目录号: A12585

库存状态:中国现货中国现货

产品名 目录号 价格 数量
MS023 5mg A12585-5
¥ 900.00
MS023 10mg A12585-10
¥ 1,500.00
MS023 25mg A12585-25
¥ 3,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

MS023 is a potent inihbitor of PRMTs 1,3,4,6,and 8 (IC50 = 30, 119, 83, 8, and 8 nM, respectively), which are responsible for asymmetric dimethylation of arginine residues.

MS023

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Chemical Information

目录号 A12585
Mechanism of action Inhibitor
分子量 287.4
化学分子式 C17H25N3O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1831110-54-3
Synonyms MS-023, MS 023
SMILES code NCCN(C)CC1=CNC=C1C2=CC=C(OC(C)C)C=C2
化学名称 N1-((4-(4-Isopropoxyphenyl)-1H-pyrrol-3-yl)methyl)-N1-methylethane-1,2-diamine

生物活性

Description
MS023 is a potent inihbitor of PRMTs 1,3,4,6,and 8 (IC50 = 30, 119, 83, 8, and 8 nM, respectively), which are responsible for asymmetric dimethylation of arginine residues.
Targets
PRMT6 PRMT8 PRMT1 PRMT4 PRMT3
4 nM5 nM30 nM83 nM119 nM

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.79 mL 173.97 mL 347.95mL
0.5 mM 6.96 mL 34.79 mL 69.59 mL
1 mM 3.48 mL 17.4 mL 34.79 mL
5 mM 0.7 mL 3.48 mL 6.96 mL

*The above data is based on the productmolecular weight 287.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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