MS4078

Name: MS4078
SKU: A20089
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A20089

ALK PROTAC degrader

MS4078 是一种针对间变性淋巴瘤激酶（ALK）的PROTAC（降解剂），其与ALK的结合亲和力 Kd 为19纳摩尔。

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
2mg	¥385.00	现货
5mg	¥630.00	现货
10mg	¥1,085.00	现货
25mg	¥1,960.00	现货
50mg	¥3,185.00	现货
100mg	¥4,725.00	现货
*10mM 1mL in DMSO**	¥1,085.00	现货
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Data Sheet

SDS

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生物活性

Discription

MS4078 is an anaplastic lymphoma kinase (ALK) PROTAC (degrader) with a Kd of 19?nM for binding affinity to ALK.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A20089
分子式	C45H52ClN9O8S
分子量	914.47
CAS号	2229036-62-6
SMILES	CC(C)S(C1=C(NC2=NC(NC3=C(OC(C)C)C=C(C4CCN(CC(NCCNC5=C(C(N(C6C(NC(CC6)=O)=O)C7=O)=O)C7=CC=C5)=O)CC4)C(C)=C3)=NC=C2Cl)C=CC=C1)(=O)=O
其他名称	MS-4078; MS4078; MS 4078
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	96 mg/mL (104.98 mM)
	Water	Insoluble
	Ethanol	2 mg/mL (2.18 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	10.94 mL	54.68 mL	109.35 mL
0.5 mM	2.19 mL	10.94 mL	21.87 mL
1 mM	1.09 mL	5.47 mL	10.94 mL
5 mM	0.22 mL	1.09 mL	2.19 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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