MS417

Name: MS417
SKU: A19433
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A19433

BRD4 抑制剂

MS417 是一种特异性针对 BET 的 BRD4 抑制剂，能够与 BRD4-BD1 和 BRD4-BD2 结合，其半抑制浓度（IC50）分别为 30, 46 nM，解离常数（Kd）分别为 36.1, 25.4 nM。该抑制剂对 CBP BRD 的选择性较弱（IC50 为 32.7 微米）。

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规格	价格	库存
1mg	¥175.00	现货
2mg	¥245.00	现货
5mg	¥385.00	现货
10mg	¥630.00	现货
25mg	¥1,050.00	现货
50mg	¥1,610.00	现货
100mg	¥2,450.00	现货
500mg	¥5,810.00	现货
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Data Sheet

SDS

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生物活性

Discription

MS417 is a BET-specific BRD4 inhibitor, binds to BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively, with weak selectivity at CBP BRD (IC50, 32.7 μM).

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A19433
分子式	C20H19ClN4O2S
分子量	414.91
CAS号	916489-36-6
SMILES	O=C(OC)C[C@H]1C2=NN=C(C)N2C3=C(C(C)=C(C)S3)C(C4=CC=C(Cl)C=C4)=N1
其他名称	GTPL-7512, GTPL 7512, GTPL7512, MS 417, MS-417
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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