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MS436

BRD4 抑制剂

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产品目录号: A13749

库存状态:中国现货中国现货

产品名 目录号 价格 数量
MS436 5mg A13749-5
¥ 1,000.00
MS436 10mg A13749-10
¥ 1,800.00
MS436 25mg A13749-25
¥ 3,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

MS436 is a diazobenzene-based small-molecule inhibitor for the BRD4 bromodomains with a Ki value of 30-50 nM.

MS436

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Chemical Information

目录号 A13749
Mechanism of action Inhibitor
分子量 383.42
化学分子式 C18H17N5O3S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1395084-25-9
Synonyms MS 436, MS-436
SMILES code CC1=C/C(=N/NC2=CC=C(C=C2)S(=O)(=O)NC3=CC=CC=N3)/C(=CC1=O)N
化学名称 4-[(2Z)-2-(2-amino-5-methyl-4-oxocyclohexa-2,5-dien-1-ylidene)hydrazinyl]-N-pyridin-2-ylbenzenesulfonamide

生物活性

Description
MS436 is a diazobenzene-based small-molecule inhibitor for the BRD4 bromodomains with a Ki value of 30-50 nM.
Targets
BRD4 (1) BRD4 (2)
<0.085 μM(Ki)0.34 μM(Ki)

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.08 mL 130.41 mL 260.81mL
0.5 mM 5.22 mL 26.08 mL 52.16 mL
1 mM 2.61 mL 13.04 mL 26.08 mL
5 mM 0.52 mL 2.61 mL 5.22 mL

*The above data is based on the productmolecular weight 383.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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