MS436
目录号: A13749
BRD4 抑制剂
MS436 是一种基于重氮苯的小分子抑制剂，针对 BRD4 溴结构域，具有 30-50 nM 的 Ki 值。
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生物活性
| Discription | MS436 is a diazobenzene-based small-molecule inhibitor for the BRD4 bromodomains with a Ki value of 30-50 nM. | |||||
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产品信息
| 目录号 | A13749 |
|---|---|
| 分子式 | C18H17N5O3S |
| 分子量 | 383.42 |
| CAS号 | 1395084-25-9 |
| SMILES | CC1=C/C(=N/NC2=CC=C(C=C2)S(=O)(=O)NC3=CC=CC=N3)/C(=CC1=O)N |
| 其他名称 | MS 436, MS-436 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 50 mg/mL (130.4 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 1 mg/mL (2.6 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.08 mL | 130.41 mL | 260.81 mL |
| 0.5 mM | 5.22 mL | 26.08 mL | 52.16 mL |
| 1 mM | 2.61 mL | 13.04 mL | 26.08 mL |
| 5 mM | 0.52 mL | 2.61 mL | 5.22 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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