MSC2530818
目录号: A12644
CDK8 抑制剂
MSC2530818 是一种效力强大、选择性高且可口服的 CDK8 抑制剂,其对 CDK8 的 IC50 为 2.6 nM。
Discription | MSC2530818 is a potent, selective and orally available CDK8 inhibitor with an IC50 of 2.6 nM for CDK8. | |||||
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Targets |
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Cell Research |
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目录号 | A12644 |
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分子式 | C18H17ClN4O |
分子量 | 340.81 |
CAS号 | 1883423-59-3 |
SMILES | O=C(N1[C@H](C2=CC=C(Cl)C=C2)CCC1)C3=CN=C(NN=C4C)C4=C3 |
其他名称 | MSC-2530818; MSC 2530818 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 66 mg/mL (193.65 mM) | |
Water | Insoluble | ||
Ethanol | 66 mg/mL (193.65 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 29.34 mL | 146.71 mL | 293.42 mL |
0.5 mM | 5.87 mL | 29.34 mL | 58.68 mL |
1 mM | 2.93 mL | 14.67 mL | 29.34 mL |
5 mM | 0.59 mL | 2.93 mL | 5.87 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2