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MT-802 is a potent BTK degrader based on PROTAC technology, with a DC50 of 1 nM. MT-802 has potential to treat C481S mutant chronic lymphocytic leukemia (CLL).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 12.69 mL | 63.47 mL | 126.93 mL |
| 0.5 mM | 2.54 mL | 12.69 mL | 25.39 mL |
| 1 mM | 1.27 mL | 6.35 mL | 12.69 mL |
| 5 mM | 0.25 mL | 1.27 mL | 2.54 mL |
*The above data is based on the productmolecular weight 787.82. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18589 |
|---|---|
| 作用机制 | Degrader (降解剂) |
| M. Wt | 787.82 |
| Formula | C41H41N9O8 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2231744-29-7 |
| Synonyms | MT802, MT 802 |
| SMILES | O=C(NC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2=O)=O)C=C1)COCCOCCN4CCC(N5N=C(C6=CC=C(OC7=CC=CC=C7)C=C6)C8=C(N)N=CN=C85)CC4 |
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