mTOR inhibitor-2
目录号: A13035
mTOR 抑制剂
mTOR inhibitor-2 是一种高效、选择性的口服 mTOR 抑制剂,其 IC50 为 7 nM。mTOR inhibitor-2 抑制细胞内 mTORC1(pS6 和 p4E-BP1)和 mTORC2(pAKT (S473))底物的磷酸化。
Discription | mTOR inhibitor-2 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR inhibitor-2 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates. | |||||
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Cell Research |
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目录号 | A13035 |
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分子式 | C23H21N7O |
分子量 | 411.46 |
CAS号 | 2219323-96-1 |
SMILES | O=C(N1C2CCN(CC#N)CC2)C=NC3=C1C4=CC(C5=CN=C(N)C=C5)=CC=C4N=C3 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2