MTX-211

Name: MTX-211
SKU: A18324
Price: 350 CNY
Rating: 5 (288 reviews)

目录号: A18324

EGFR/PI3K dual 抑制剂

MTX-211 是一种 EGFR 和 PI3K 的双重抑制剂，这两种酶在 KRAS 突变型结直肠癌的进展中扮演着重要角色。MTX-211 对于治疗 KRAS 突变型结直肠癌具有潜在的应用价值。

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Grouped product items
规格	价格	库存
1mg	¥350.00	现货
2mg	¥630.00	现货
5mg	¥1,330.00	现货
10mg	¥2,030.00	现货
25mg	¥3,395.00	现货
50mg	¥4,690.00	现货
100mg	¥6,370.00	现货
200mg	¥8,505.00	现货
*10mM 1mL in DMSO**	¥1,365.00	现货
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Data Sheet

SDS

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生物活性

Discription

MTX-211 is a dual inhibitor of EGFR and PI3K, which plays important roles in the progression of KRAS mutant colorectal cancer. MTX-211 has the potential for the treatment of KRAS mutant colorectal cancer.

Targets

Target	Value

产品信息

目录号	A18324
分子式	C20H14Cl2FN5O2S
分子量	478.3234
CAS号	1952236-05-3
SMILES	CS(=O)(NC1=CC(C2=CC3=C(NC4=CC=C(F)C(Cl)=C4)N=CN=C3C=C2)=CN=C1Cl)=O
其他名称	MTX211, MTX 211
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	22 mg/mL (45.99 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.91 mL	104.53 mL	209.06 mL
0.5 mM	4.18 mL	20.91 mL	41.81 mL
1 mM	2.09 mL	10.45 mL	20.91 mL
5 mM	0.42 mL	2.09 mL	4.18 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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