Mutant IDH1-IN-1

Name: Mutant IDH1-IN-1
SKU: A21359

目录号: A21359

mutant-selective IDH1 inhibitor

Mutant IDH1-IN-1 Chemical Structure

CAS NO. 1355326-21-4

Mutant IDH1-IN-1 is a mutant-selective IDH1 inhibitor with with IC50s of 4, 42, 80 and 143 nM against mutant IDH1 R132C/R132C, IDH1 R132H/R132H, IDH1 R132H/WT and wild type IDH1, respectively.

库存：现货

规格	价格	数量
5 mg	￥ 1,710.00
10 mg	￥ 2,950.00
50 mg	￥ 8,740.00
100 mg	￥ 17,480.00

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生物活性

Mutant IDH1-IN-1 is a mutant-selective IDH1 inhibitor with with IC50s of 4, 42, 80 and 143 nM against mutant IDH1 R132C/R132C, IDH1 R132H/R132H, IDH1 R132H/WT and wild type IDH1, respectively.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.06 mL	100.28 mL	200.57 mL
0.5 mM	4.01 mL	20.06 mL	40.11 mL
1 mM	2.01 mL	10.03 mL	20.06 mL
5 mM	0.4 mL	2.01 mL	4.01 mL

*The above data is based on the productmolecular weight 498.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A21359
作用机制	Inhibitor (抑制剂)
M. Wt	498.59
Formula	C30H31FN4O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1355326-21-4
SMILES	O=C(C(C1=C(C)C=CC=C1)N(C(CN2C=NC3=C2C=CC=C3)=O)C4=CC(F)=CC=C4)NC5CCCCC5