Mutant IDH1-IN-4

目录号: A19106

IDH1 inhibitor

Mutant IDH1-IN-4

Mutant IDH1-IN-4 Chemical Structure

CAS NO. 1416270-18-2

Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ?? 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells.

库存: 现货

规格 价格 数量
1 mg
¥ 2,700.00
5 mg
¥ 8,100.00
10 mg
¥ 13,800.00
50 mg
¥ 41,400.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ?? 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.8 mL 114.01 mL 228.02 mL
0.5 mM 4.56 mL 22.8 mL 45.6 mL
1 mM 2.28 mL 11.4 mL 22.8 mL
5 mM 0.46 mL 2.28 mL 4.56 mL

*The above data is based on the productmolecular weight 438.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A19106
作用机制 Inhibitor (抑制剂)
M. Wt 438.56
Formula C25H34N4O3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1416270-18-2
SMILES N#CC1=C(N2C[C@@H](C3CC3)N(C(CCOC)=O)CC2)N=C(C4CC4)C5=C1CC(C)(C)OC5

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