Mycophenolate mofetil (CellCept)
目录号: A10613
IMPDH 抑制剂
Mycophenolate mofetil 是一种可逆的肌苷酸单磷酸脱氢酶(IMPDH)抑制剂,用于嘌呤生物合成中(特别是鸟嘌呤合成),这对于T细胞和B细胞的生长是必需的。
| Discription | Mycophenolate mofetil is a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH) in purine biosynthesis (specifically guanine synthesis) which is necessary for the growth of T cells and B cells. | |||||
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| Cell Research |
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| 目录号 | A10613 |
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| 分子式 | C23H31NO7 |
| 分子量 | 433.5 |
| CAS号 | 128794-94-5 |
| SMILES | CC1=C(C(=C(C2=C1COC2=O)O)C/C=C(\C)/CCC(=O)OCCN3CCOCC3)OC |
| 其他名称 | RS 61443, TM-MMF |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 77 mg/mL (177.62 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 0.5% methylcellulose | 19 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.07 mL | 115.34 mL | 230.68 mL |
| 0.5 mM | 4.61 mL | 23.07 mL | 46.14 mL |
| 1 mM | 2.31 mL | 11.53 mL | 23.07 mL |
| 5 mM | 0.46 mL | 2.31 mL | 4.61 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2