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MZ1是BRD2和BRD3上BRD4可逆，持久和选择性去除的有效诱导剂。
| In vitro | DMSO | 97 mg/mL (96.74 mM) | |
| Water | Insoluble | ||
| Ethanol | 97 mg/mL (96.74 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 9.97 mL | 49.87 mL | 99.74 mL |
| 0.5 mM | 1.99 mL | 9.97 mL | 19.95 mL |
| 1 mM | 1 mL | 4.99 mL | 9.97 mL |
| 5 mM | 0.2 mL | 1 mL | 1.99 mL |
*The above data is based on the productmolecular weight 1002.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A17014 |
|---|---|
| 作用机制 | Degrader (降解剂) |
| M. Wt | 1002.64 |
| Formula | C49H60ClN9O8S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1797406-69-9 |
| Synonyms | MZ-1, MZ 1 |
| SMILES | CC1=C(C)SC2=C1C(C3=CC=C(Cl)C=C3)=N[C@@H](CC(NCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N4[C@@H](C[C@@H](O)C4)C(NCC5=CC=C(C6=C(N=CS6)C)C=C5)=O)=O)=O)=O)C7=NN=C(C)N27 |
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