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Acetylglucosamine or N-acetylglucosamine is potentially for the treatment of irritable bowel syndrome. N-Acetylglucosamine (GlcNAc) is a monosaccharide that usually polymerizes linearly through (1,4)-β-linkages. GlcNAc has been reported to be an inhibitor of elastase release from human polymorphonuclear leukocytes (range 8?C17% inhibition), however this is much weaker than the inhibition seen with N-acetylgalactosamine (range 92?C100%).
| In vitro | DMSO | 43 mg/mL (194.38 mM) | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 45.21 mL | 226.03 mL | 452.06 mL |
| 0.5 mM | 9.04 mL | 45.21 mL | 90.41 mL |
| 1 mM | 4.52 mL | 22.6 mL | 45.21 mL |
| 5 mM | 0.9 mL | 4.52 mL | 9.04 mL |
*The above data is based on the productmolecular weight 221.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A17841 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 221.21 |
| Formula | C8H15NO6 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 7512-17-6 |
| Synonyms | Acetylglucosamine; GlcNAc; Bio-NAG; GreenNAG; Marine Sweet; N-Acetyl-D-glucosamine; N-Acetylglucosamine; NSC 400525; NSC 524344. |
| SMILES | O[C@H]1[C@@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)NC(C)=O |
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