Naftopidil 2HCl

目录号: A10619

5-HT1A and α1-adrenergic receptor antagonist

Naftopidil 2HCl

Naftopidil 2HCl Chemical Structure

CAS NO. 57149-08-3

Naftopidil 2HCl is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.

库存: 现货

规格 价格 数量
25 mg
¥ 350.00
50 mg
¥ 500.00
100 mg
¥ 900.00
500 mg
¥ 3,300.00
10mM * 1mL in DMSO
¥ 660.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Naftopidil 2HCl is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.
Targets
5-HT1A α1-adrenergic receptor
0.1 μM0.2 μM
In vitro (25°C) DMSO 41 mg/mL (88.09 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (4.29 mM)
In vivo 0.5% CMC 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.49 mL 107.43 mL 214.87 mL
0.5 mM 4.3 mL 21.49 mL 42.97 mL
1 mM 2.15 mL 10.74 mL 21.49 mL
5 mM 0.43 mL 2.15 mL 4.3 mL

*The above data is based on the productmolecular weight 465.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A10619
MECHANISM OF ACTION Antagonist
M. Wt 465.4
Formula C24H28N2O3.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 57149-08-3
Synonyms Flivas, KT-611, Avishot
SMILES COC1=CC=CC=C1N2CCN(CC2)CC(COC3=CC=CC4=CC=CC=C43)O.Cl.Cl

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