Naluzotan
目录号: A22028
5-HT1A 激动剂
Naluzotan 是一种新型、高效、选择性的 酰胺磺酰胺类 5-HT1A 激动剂,其 IC50 和 Ki 分别约为 20 nM 和 5.1 nM,用于治疗焦虑和抑郁症;同时也是一种弱 hERG K+ 通道阻断剂,其 IC50 为 3800 nM。
Discription | Naluzotan is a novel, potent, and selective amidosulfonamide 5-HT1A agonist with IC50 and Ki of appr 20 nM and 5.1 nM, used for the treatment of anxiety and depression; Also a weak hERG K+ channel blocker, with IC50 of 3800 nM. | |||||
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Cell Research |
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目录号 | A22028 |
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分子式 | C23H38N4O3S |
分子量 | 450.64 |
CAS号 | 740873-06-7 |
SMILES | CC(NC1=CC=CC(N2CCN(CCCCNS(=O)(CC3CCCCC3)=O)CC2)=C1)=O |
其他名称 | PRX 00023, PRX00023, PRX-00023 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2