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Naquotinib mesylate

Naquotinib mesylate

Name: Naquotinib mesylate
SKU: A20762

目录号: A20762

EGFR inhibitor

Naquotinib mesylate Chemical Structure

CAS NO. 1448237-05-5

Naquotinib mesylate (ASP8273 mesylate) is an orally available, mutant-selective and irreversible EGFR inhibitor; with IC50s of 8-33 nM toward EGFR mutants and 230 nM for EGFR.

库存：现货

规格	价格	数量
1 mg	￥ 810.00
5 mg	￥ 2,430.00
10 mg	￥ 4,140.00
50 mg	￥ 12,420.00

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生物活性

Naquotinib mesylate (ASP8273 mesylate) is an orally available, mutant-selective and irreversible EGFR inhibitor; with IC50s of 8-33 nM toward EGFR mutants and 230 nM for EGFR.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	15.18 mL	75.89 mL	151.79 mL
0.5 mM	3.04 mL	15.18 mL	30.36 mL
1 mM	1.52 mL	7.59 mL	15.18 mL
5 mM	0.3 mL	1.52 mL	3.04 mL

*The above data is based on the productmolecular weight 658.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A20762
M. Wt	658.81
Formula	C31H46N8O6S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1448237-05-5
Synonyms	ASP8273 (mesylate), ASP 8273, ASP-8273
SMILES	O=C(C1=NC(CC)=C(O[C@H]2CN(C(C=C)=O)CC2)N=C1NC3=CC=C(N4CCC(N5CCN(C)CC5)CC4)C=C3)N.CS(=O)(O)=O