Naratuximab is a humanized monoclonal antibody specifically targeting CD37 (TSPAN26), a tetraspanin protein widely expressed on the surface of B cells. This antibody exhibits high specificity and affinity for CD37, making it an ideal candidate for targeted therapeutic applications, including the development of antibody-drug conjugates (ADCs). Naratuximab serves as the foundation for the ADC compound Naratuximab emtansine, which combines the targeted binding properties of naratuximab with the cytotoxic agent emtansine, offering potential applications in the treatment of B-cell malignancies.
Naratuximab is a humanized monoclonal antibody specifically targeting CD37 (TSPAN26), a tetraspanin protein widely expressed on the surface of B cells. This antibody exhibits high specificity and affinity for CD37, making it an ideal candidate for targeted therapeutic applications, including the development of antibody-drug conjugates (ADCs). Naratuximab serves as the foundation for the ADC compound Naratuximab emtansine, which combines the targeted binding properties of naratuximab with the cytotoxic agent emtansine, offering potential applications in the treatment of B-cell malignancies.
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