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Nebivolol HCl

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产品目录号: A10630

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Nebivolol HCl 10mg A10630-10
¥ 500.00
Nebivolol HCl 25mg A10630-25
¥ 750.00
Nebivolol HCl 50mg A10630-50
¥ 1,200.00
Nebivolol HCl 100mg A10630-100
¥ 2,000.00
Nebivolol HCl 10mM * 1mL in DMSO A10630-10mM-D
¥ 550.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Nebivolol hydrochloride is t a highly selective antagonist of the β1-adrenoceptor (Ki = 0.88 nM, β2-adrenoceptor Ki = 48 nM).

Nebivolol HCl

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Chemical Information

目录号 A10630
Mechanism of action N/A
分子量 441.9
化学分子式 C22H25F2NO4.HCl
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 152520-56-4
Synonyms R-67145
SMILES code C1CC2=C(C=CC(=C2)F)O[C@H]1[C@H](CNC[C@@H]([C@@H]3CCC4=C(O3)C=CC(=C4)F)O)O.Cl
化学名称 alpha,alpha'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol hydrochloride

生物活性

Description
Nebivolol hydrochloride is t a highly selective antagonist of the β1-adrenoceptor (Ki = 0.88 nM, β2-adrenoceptor Ki = 48 nM).
Targets
β1-adrenoceptor
0.8 nM

溶解性

Solubility (25°C)* In vitro DMSO 88 mg/mL (199.14 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.63 mL 113.15 mL 226.3mL
0.5 mM 4.53 mL 22.63 mL 45.26 mL
1 mM 2.26 mL 11.31 mL 22.63 mL
5 mM 0.45 mL 2.26 mL 4.53 mL

*The above data is based on the productmolecular weight 441.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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