Necrostatin-1

目录号: A11973

RIPK1 inhibitor

Necrostatin-1 Chemical Structure

CAS NO. 4311-88-0

Necrostatin-1 is an ATP-competitive, allosteric inhibitor of receptor-interacting protein kinase 1 (RIPK1) (EC50 = 182 nM).

库存: 现货

规格 价格 数量
10 mg
¥ 500.00
25 mg
¥ 900.00
50 mg
¥ 1,500.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Necrostatin-1 is an ATP-competitive, allosteric inhibitor of receptor-interacting protein kinase 1 (RIPK1) (EC50 = 182 nM).
Targets
RIP1 (293T cells)
490 nM(EC50)
In vitro DMSO 52 mg/mL (200.51 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 38.56 mL 192.8 mL 385.61 mL
0.5 mM 7.71 mL 38.56 mL 77.12 mL
1 mM 3.86 mL 19.28 mL 38.56 mL
5 mM 0.77 mL 3.86 mL 7.71 mL

*The above data is based on the productmolecular weight 259.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11973
MECHANISM OF ACTION Inhibitor
M. Wt 259.33
Formula C13H13N3OS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 4311-88-0
Synonyms N/A
SMILES CN1C(=O)C(NC1=S)CC2=CNC3=CC=CC=C32

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