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Necrosulfonamide

目录号: A16334
MLKL 抑制剂
Necrosulfonamide 是一种针对 MLKL 的药理抑制剂,其在人类 HT-29 细胞中的 IC50 值为 124 nM。
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5mg
¥315.00
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10mg
¥420.00
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25mg
¥945.00
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50mg
¥1,540.00
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100mg
¥2,730.00
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500mg
¥6,545.00
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10mM * 1mL in DMSO
¥315.00
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用Necrosulfonamide发表的1篇文献
  • Cheng Chen, .et al. , Neurochem Res, 2025, Mar 18;50(2):122 PMID: 40100474
  • 生物活性
    Discription Necrosulfonamide is a pharmacological inhibitor of MLKL with IC50 values of 124 nM in human HT-29.
    产品信息
    目录号 A16334
    分子式 C18H15N5O6S2
    分子量 461.47
    CAS号 1360614-48-7
    SMILES O=S(NC1=NC=CN=C1OC)(C(C=C2)=CC=C2NC(/C=C\C3=CC=C([N+]([O-])=O)S3)=O)=O
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro DMSO 78 mg/mL (169.02 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.67 mL 108.35 mL 216.7 mL
    0.5 mM 4.33 mL 21.67 mL 43.34 mL
    1 mM 2.17 mL 10.83 mL 21.67 mL
    5 mM 0.43 mL 2.17 mL 4.33 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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