Nefazodone hydrochloride
目录号: A17622
5-HT2 receptors 抑制剂
Nefazodone HCl 是一种用于治疗情绪障碍的药物,它抑制 5-HT2 受体、SERT、NET 和 hERG K+ 通道。它能减少强迫游泳测试中的不动时间。
Discription | Nefazodone HCl is an inhibitor of 5-HT2 receptors, SERT, NET, and hERG K+ channels used to treat mood disorders. It decreases immobility time in the forced swim test. | ||
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目录号 | A17622 |
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分子式 | C25H33Cl2N5O2 |
分子量 | 506.47 |
CAS号 | 82752-99-6 |
SMILES | O=C1N(CCCN2CCN(C3=CC=CC(Cl)=C3)CC2)N=C(CC)N1CCOC4=CC=CC=C4.[H]Cl |
其他名称 | BMY 13754; BMY13754; BMY-13754; Dutonin; Nefazodone HCl; Rulivan; MJ 13754 1; MJ-13754-1; MJ137541 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 19 mg/mL (37.51 mM) | |
Ethanol | <1 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 19.74 mL | 98.72 mL | 197.45 mL |
0.5 mM | 3.95 mL | 19.74 mL | 39.49 mL |
1 mM | 1.97 mL | 9.87 mL | 19.74 mL |
5 mM | 0.39 mL | 1.97 mL | 3.95 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2