Neihulizumab (ALTB-168) functions as an agonistic antibody targeting the immune checkpoint receptor CD162, also known as PSGL-1. By binding to this receptor, Neihulizumab effectively mediates the downregulation of activated T-cells. This antibody is primarily utilized in research focusing on steroid-refractory acute graft-versus-host disease (SR-aGVHD), as well as studies related to psoriasis, psoriatic arthritis, and ulcerative colitis. Its unique mechanism and specificity make it a valuable tool in the investigation of immune response modulation in these conditions.
Neihulizumab (ALTB-168) functions as an agonistic antibody targeting the immune checkpoint receptor CD162, also known as PSGL-1. By binding to this receptor, Neihulizumab effectively mediates the downregulation of activated T-cells. This antibody is primarily utilized in research focusing on steroid-refractory acute graft-versus-host disease (SR-aGVHD), as well as studies related to psoriasis, psoriatic arthritis, and ulcerative colitis. Its unique mechanism and specificity make it a valuable tool in the investigation of immune response modulation in these conditions.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
