Nelarabine (Arranon)

目录号: A10632

Nelarabine (Arranon)

Nelarabine (Arranon) Chemical Structure

CAS NO. 121032-29-9

Nelarabine是一种嘌呤核苷类似物,可转化为其相应的阿拉伯糖基鸟嘌呤核苷酸三磷酸(araGTP),从而抑制DNA合成和细胞毒性,IC50为0.067-2.15 μM。

库存: 现货

规格 价格 数量
5 mg
¥ 700.00
10 mg
¥ 1,200.00
50 mg
¥ 4,000.00
100 mg
¥ 5,800.00
10mM * 1mL in DMSO
¥ 800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Nelarabine是一种嘌呤核苷类似物,可转化为其相应的阿拉伯糖基鸟嘌呤核苷酸三磷酸(araGTP),从而抑制DNA合成和细胞毒性,IC50为0.067-2.15 μM。
靶点信息
DNA synthesis (PER-255 cells) DNA synthesis (HSB2 cells) DNA synthesis (ALL-SIL cells) DNA synthesis (JURKAT cells)
67 nM0.44 μM1.24 μM2.15 μM
In vitro (25°C) DMSO 55 mg/mL (185.01 mM)
Water 3 mg/mL (10.09 mM)
Ethanol Insoluble
In vivo saline 2 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.64 mL 168.18 mL 336.36 mL
0.5 mM 6.73 mL 33.64 mL 67.27 mL
1 mM 3.36 mL 16.82 mL 33.64 mL
5 mM 0.67 mL 3.36 mL 6.73 mL

*The above data is based on the productmolecular weight 297.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10632
M. Wt 297.3
Formula C11H15N5O5
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 121032-29-9
Synonyms 506U78
SMILES COC1=NC(=NC2=C1N=CN2[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)O)N

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