Nepicastat (free base) (SYN-117)
目录号: A10637
dopamine beta-hydroxylase 抑制剂
Nepicastat 是一种多巴胺β-羟化酶的抑制剂,这种酶催化多巴胺转化为去甲肾上腺素。
| Discription | Nepicastat is an inhibitor of dopamine beta-hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine. |
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| 目录号 | A10637 |
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| 分子式 | C14H15F2N3S |
| 分子量 | 295.4 |
| CAS号 | 173997-05-2 |
| SMILES | C1CC2=C(C=C(C=C2C[C@H]1N3C(=CNC3=S)CN)F)F |
| 其他名称 | RS-25560-197 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 61 mg/mL (183.83 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 33.85 mL | 169.26 mL | 338.52 mL |
| 0.5 mM | 6.77 mL | 33.85 mL | 67.7 mL |
| 1 mM | 3.39 mL | 16.93 mL | 33.85 mL |
| 5 mM | 0.68 mL | 3.39 mL | 6.77 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2