|Mechanism of action||Antagonist|
|储存方式||at -20°C 2 years|
|Netupitant is a selective neurokinin 1 (NK1) receptor antagonist. It competitively binds to and blocks the activity of the human substance P/NK1 receptors in the central nervous system (CNS), thereby inhibiting NK1-receptor binding of the endogenous tachykinin neuropeptide substance P (SP), which may result in the prevention of chemotherapy-induced nausea and vomiting (CINV).|
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||17.28 mL||86.42 mL||172.83mL|
|0.5 mM||3.46 mL||17.28 mL||34.57 mL|
|1 mM||1.73 mL||8.64 mL||17.28 mL|
|5 mM||0.35 mL||1.73 mL||3.46 mL|
*The above data is based on the productmolecular weight 578.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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