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Nevanimibe hydrochloride (PD-132301 hydrochloride; ATR101 hydrochloride) is a selective and potent acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.83 mL | 109.15 mL | 218.3 mL |
| 0.5 mM | 4.37 mL | 21.83 mL | 43.66 mL |
| 1 mM | 2.18 mL | 10.92 mL | 21.83 mL |
| 5 mM | 0.44 mL | 2.18 mL | 4.37 mL |
*The above data is based on the productmolecular weight 458.08. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21767 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 458.08 |
| Formula | C27H40ClN3O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 133825-81-7 |
| Synonyms | PD-132301 hydrochloride, PD132301, PD 132301; ATR101 hydrochloride, ATR 101, ATR-101 |
| SMILES | O=C(NCC1(C2=CC=C(N(C)C)C=C2)CCCC1)NC3=C(C(C)C)C=CC=C3C(C)C.[H]Cl |
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