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NF 279

P2X1 拮抗剂

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产品目录号: A11972


产品名 目录号 价格 数量
NF 279 10mg A11972-10
¥ 1,200.00
NF 279 25mg A11972-25
¥ 2,500.00
NF 279 50mg A11972-50
¥ 4,200.00



NF279 is a suramin analog that acts as a highly selective, competitive, and reversible ATP-antagonist of P2X receptor (IC50/KB ~ 1 μM in smooth muscle).

NF 279




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Chemical Information

目录号 A11972
Mechanism of action Antagonist
分子量 1401.1
化学分子式 C49H30N6Na6O23S6
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 202983-32-2
Synonyms NF279, NF-279
SMILES code C1=CC(=CC=C1C(=O)NC2=C3C(=CC(=CC3=C(C=C2)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])NC(=O)C4=CC=C(C=C4)NC(=O)NC5=CC=C(C=C5)C(=O)NC6=CC=C(C=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
化学名称 8,8'-[Carbonylbis(imino-4,1-phenylen?ecarbonylimino-4,1-phenylenecarbonylimino)]bis-1,3?,5-naphthalenetrisulfonic acid hexasodium salt


NF279 is a suramin analog that acts as a highly selective, competitive, and reversible ATP-antagonist of P2X receptor (IC50/KB ~ 1 μM in smooth muscle).


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 7.14 mL 35.69 mL 71.37mL
0.5 mM 1.43 mL 7.14 mL 14.27 mL
1 mM 0.71 mL 3.57 mL 7.14 mL
5 mM 0.14 mL 0.71 mL 1.43 mL

*The above data is based on the productmolecular weight 1401.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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