NG25
目录号: A15185
TAK1/MAP4K2 抑制剂
NG25，一种TAK1抑制剂，抑制了TLR7和TLR9激动剂对IKK的激活，并阻止了这些配体在Gen2.2细胞中诱导的1型IFNs的分泌。
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生物活性
| Discription | NG25, a TAK1 inhibitor, inhibited the activation of IKK by TLR7 and TLR9 agonists and prevented the secretion of type 1 IFNs induced by these ligands in Gen2.2 cells. | ||
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产品信息
| 目录号 | A15185 |
|---|---|
| 分子式 | C29H30F3N5O2 |
| 分子量 | 537.58 |
| CAS号 | 1315355-93-1 |
| SMILES | CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)OC4=C5C=CNC5=NC=C4)C(F)(F)F |
| 其他名称 | NG 25, NG-25 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 85 mg/mL (158.11 mM) | |
| Water | Insoluble | ||
| Ethanol | 2 mg/mL (3.72 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.6 mL | 93.01 mL | 186.02 mL |
| 0.5 mM | 3.72 mL | 18.6 mL | 37.2 mL |
| 1 mM | 1.86 mL | 9.3 mL | 18.6 mL |
| 5 mM | 0.37 mL | 1.86 mL | 3.72 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1315355-93-1 | 1315355-93-1 供应商 | 1315355-93-1 花费 | 1315355-93-1 生产商 | 订购 1315355-93-1 | 1315355-93-1 代理商