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NG25

TAK1/MAP4K2 抑制剂

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产品目录号: A15185

库存状态:中国现货中国现货

产品名 目录号 价格 数量
NG25 5mg A15185-5
¥ 2,250.00
NG25 10mg A15185-10
¥ 4,250.00
NG25 25mg A15185-25
¥ 8,250.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

NG25, a TAK1 inhibitor, inhibited the activation of IKK by TLR7 and TLR9 agonists and prevented the secretion of type 1 IFNs induced by these ligands in Gen2.2 cells.

NG25

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Chemical Information

目录号 A15185
Mechanism of action Inhibitor
分子量 537.58
化学分子式 C29H30F3N5O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1315355-93-1
Synonyms NG 25, NG-25
SMILES code CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)OC4=C5C=CNC5=NC=C4)C(F)(F)F
化学名称 N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide

生物活性

Description
NG25, a TAK1 inhibitor, inhibited the activation of IKK by TLR7 and TLR9 agonists and prevented the secretion of type 1 IFNs induced by these ligands in Gen2.2 cells.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.6 mL 93.01 mL 186.02mL
0.5 mM 3.72 mL 18.6 mL 37.2 mL
1 mM 1.86 mL 9.3 mL 18.6 mL
5 mM 0.37 mL 1.86 mL 3.72 mL

*The above data is based on the productmolecular weight 537.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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