NGP-555

Name: NGP-555
SKU: A17051

目录号: A17051

γ-Secretase Modulator

NGP-555 Chemical Structure

CAS NO. 1304630-27-0

NGP-555是一种γ-分泌酶调节剂，具有选择性机制，可减少Abeta 42，同时提高较短的Abeta形式，例如Abeta 37和38。

库存：现货

规格	价格	数量
5 mg	￥ 2,000.00
10 mg	￥ 3,800.00
50 mg	￥ 12,000.00
100 mg	￥ 19,800.00

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生物活性

NGP-555是一种γ-分泌酶调节剂，具有选择性机制，可减少Abeta 42，同时提高较短的Abeta形式，例如Abeta 37和38。

溶解度 *

In vitro	DMSO	38 mg/mL (93.47 mM)
	Water	Insoluble
	Ethanol	3 mg/mL (7.37 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.6 mL	123 mL	245.99 mL
0.5 mM	4.92 mL	24.6 mL	49.2 mL
1 mM	2.46 mL	12.3 mL	24.6 mL
5 mM	0.49 mL	2.46 mL	4.92 mL

*The above data is based on the productmolecular weight 406.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A17051
作用机制	Modulator (调节剂)
M. Wt	406.52
Formula	C23H23FN4S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1304630-27-0
Synonyms	NGP555, NGP 555
SMILES	FC1=CC(C2=CSC(NC3=CC(CC)=C(C)C=C3C)=N2)=CC=C1N4C=C(C)N=C4