NI-42

Name: NI-42
SKU: A20599
Price: 140 CNY
Rating: 5 (288 reviews)

目录号: A20599

BRD 抑制剂

NI-42（化合物13-d），是一种针对BRPFs的结构正交化学探针，是一种有偏见的、强效的BRPFs的BRD（溴结构域）抑制剂（BRPF1/2/3的IC50分别为7.9/48/260 nM；BRPF1/2/3的Kd值分别为40/210/940 nM），具有对非第四类BRD蛋白的优异选择性。

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Grouped product items
规格	价格	库存
1mg	¥140.00	现货
5mg	¥210.00	现货
10mg	¥385.00	现货
25mg	¥840.00	现货
50mg	¥1,330.00	现货
100mg	¥2,100.00	现货
*10mM 1mL in DMSO**	¥245.00	现货
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Data Sheet

SDS

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生物活性

Discription

NI-42 (compound 13-d), a structurally orthogonal chemical probe for the BRPFs, is a biased, potent inhibitor of the BRD of the BRPFs (IC50s of BRPF1/2/3=7.9/48/260 nM; Kds of BRPF1/2/3=40/210/940 nM) with excellent selectivity over nonclass IV BRD proteins.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A20599
分子式	C18H15N3O3S
分子量	353.4
CAS号	1884640-99-6
SMILES	O=S(C1=CC=C(C#N)C=C1)(NC2=CC=C(N(C)C(C(C)=C3)=O)C3=C2)=O
其他名称	NI42, NI 42
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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