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Nivocasan (GS-9450)

Caspase 抑制剂

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产品目录号: A14100

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Nivocasan 5mg A14100-5
¥ 2,200.00
Nivocasan 10mg A14100-10
¥ 5,000.00
Nivocasan 25mg A14100-25
¥ 8,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Nivocasan is a novel caspase-inhibitor has demonstrated hepatoprotective activity in fibrosis/apoptosis animal models.

Nivocasan (GS-9450)

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Chemical Information

目录号 A14100
Mechanism of action Inhibitor
分子量 415.41
化学分子式 C21H22FN3O5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 908253-63-4
Synonyms GS 9450,LB 84451 GS 9450,LB 84451
SMILES code CC(C)[C@]1(CC(=NO1)C2=CC=CC3=C2C=NC=C3)C(=O)N[C@H]4CC(=O)O[C@@]4(CF)O
化学名称 (R)-N-((2S,3S)-2-(fluoromethyl)-2-hydroxy-5-oxotetrahydrofuran-3-yl)-5-isopropyl-3-(isoquinolin-1-yl)-4,5-dihydroisoxazole-5-carboxamide

生物活性

Description
Nivocasan is a novel caspase-inhibitor has demonstrated hepatoprotective activity in fibrosis/apoptosis animal models.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.07 mL 120.36 mL 240.73mL
0.5 mM 4.81 mL 24.07 mL 48.15 mL
1 mM 2.41 mL 12.04 mL 24.07 mL
5 mM 0.48 mL 2.41 mL 4.81 mL

*The above data is based on the productmolecular weight 415.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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