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NK314

Topoisomerase II 抑制剂

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产品目录号: A13993

库存状态:中国现货中国现货

产品名 目录号 价格 数量
NK314 5mg A13993-5
¥ 2,200.00
NK314 10mg A13993-10
¥ 4,000.00
NK314 25mg A13993-25
¥ 9,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

NK314 is a novel synthetic benzo[c]phenanthridine alkaloid that shows strong antitumor activity. It inhibited topoisomerase II activity and stabilized topoisomerase II-DNA cleavable complexes.

NK314

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Chemical Information

目录号 A13993
Mechanism of action Inhibitor
分子量 395.83
化学分子式 C22H18ClNO4
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 208237-49-4
Synonyms NK-314, NK 314
SMILES code OC1=C(OC)C=CC2=C(C=CC3C4C=C5C(OCO5)=C3)C4=[N+]6C(CCC6)=C12.[Cl-]
化学名称 4-hydroxy-5-methoxy-2,3-dihydro-1H-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]pyrrolo[1,2-f]phenanthridin-12-ium chloride

生物活性

Description
NK314 is a novel synthetic benzo[c]phenanthridine alkaloid that shows strong antitumor activity. It inhibited topoisomerase II activity and stabilized topoisomerase II-DNA cleavable complexes.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.26 mL 126.32 mL 252.63mL
0.5 mM 5.05 mL 25.26 mL 50.53 mL
1 mM 2.53 mL 12.63 mL 25.26 mL
5 mM 0.51 mL 2.53 mL 5.05 mL

*The above data is based on the productmolecular weight 395.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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