NKL 22
目录号: A20600
HDAC 抑制剂
NKL 22 是一种 HDAC 抑制剂。其 IC 50 值为 78 uM。NKL 22 可增加 frataxin 蛋白浓度。NKL 22 抑制剂可增加 FRDA 淋巴细胞中的 FXN mRNA。HDAC 抑制剂 直接作用于 FXN。
Discription | NKL 22 is a HDAC inhibitor. The value of IC 50 is 78 uM NKL 22 increase frataxin protein concentrations NKL 22 inhibitors increase FXN mRNA in FRDA lymphocytes. HDAC inhibitors act directly on FXN. | |||||
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Cell Research |
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目录号 | A20600 |
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分子式 | C19H23N3O2 |
分子量 | 325.4 |
CAS号 | 537034-15-4 |
SMILES | O=C(NC1=CC=CC=C1N)CCCCCC(NC2=CC=CC=C2)=O |
其他名称 | NKL22, NKL-22 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 62 mg/mL (190.53 mM) | |
Water | Insoluble | ||
Ethanol | 3 mg/mL (9.21 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 30.73 mL | 153.66 mL | 307.31 mL |
0.5 mM | 6.15 mL | 30.73 mL | 61.46 mL |
1 mM | 3.07 mL | 15.37 mL | 30.73 mL |
5 mM | 0.61 mL | 3.07 mL | 6.15 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2