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NLG919

促销

IDO 抑制剂

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产品目录号: A14322

库存状态:中国现货中国现货

产品名 目录号 价格 数量
NLG919 25mg A14322-25
¥ 1,800.00
NLG919 50mg A14322-50
¥ 2,400.00
NLG919 100mg A14322-100
¥ 4,200.00
NLG919 10mM * 1mL in DMSO A14322-10mM-D
¥ 790.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

NLG919 is an orally available inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), with potential immunomodulating and antineoplastic activities.

NLG919

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Chemical Information

目录号 A14322
Mechanism of action Inhibitor
分子量 282.38
化学分子式 C18H22N2O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1402836-58-1
Synonyms NLG 919, NLG-919
SMILES code C1CCC(CC1)C(CC2C3=CC=CC=C3C4=CN=CN24)O
化学名称 1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol

生物活性

Description
NLG919 is an orally available inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), with potential immunomodulating and antineoplastic activities.
Targets
IDO (Cell-free assay) IDO (Cell-free assay)
75 nM(EC50)75 nM(EC50)

溶解性

Solubility (25°C)* In vitro DMSO 15 mg/mL heating (53.11 mM)
Water <1 mg/mL (<1 mM)
Ethanol 56 mg/mL heating (198.31 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.41 mL 177.07 mL 354.13mL
0.5 mM 7.08 mL 35.41 mL 70.83 mL
1 mM 3.54 mL 17.71 mL 35.41 mL
5 mM 0.71 mL 3.54 mL 7.08 mL

*The above data is based on the productmolecular weight 282.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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