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IDO 抑制剂

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产品目录号: A14322


产品名 目录号 价格 数量
NLG919 25mg A14322-25
¥ 1,800.00
NLG919 50mg A14322-50
¥ 2,400.00
NLG919 100mg A14322-100
¥ 4,200.00
NLG919 10mM * 1mL in DMSO A14322-10mM-D
¥ 790.00



NLG919 is an orally available inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), with potential immunomodulating and antineoplastic activities.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A14322
Mechanism of action Inhibitor
分子量 282.38
化学分子式 C18H22N2O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1402836-58-1
Synonyms NLG 919, NLG-919
化学名称 1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol


NLG919 is an orally available inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), with potential immunomodulating and antineoplastic activities.
IDO (Cell-free assay) IDO (Cell-free assay)
75 nM(EC50)75 nM(EC50)


Solubility (25°C)* In vitro DMSO 15 mg/mL heating (53.11 mM)
Water <1 mg/mL (<1 mM)
Ethanol 56 mg/mL heating (198.31 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.41 mL 177.07 mL 354.13mL
0.5 mM 7.08 mL 35.41 mL 70.83 mL
1 mM 3.54 mL 17.71 mL 35.41 mL
5 mM 0.71 mL 3.54 mL 7.08 mL

*The above data is based on the productmolecular weight 282.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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