NMS-1286937

目录号: A13045

PLK inhibitor

NMS-1286937

NMS-1286937 Chemical Structure

CAS NO. 1034616-18-6

NMS-1286937 is an orally bioavailable, small-molecule Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic activity.

库存: 现货

规格 价格 数量
10 mg
¥ 1,200.00
25 mg
¥ 2,500.00
50 mg
¥ 4,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

NMS-1286937 is an orally bioavailable, small-molecule Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic activity.
Targets
PLK1 PLK2 PLK3
2 nM>10 μM>10 μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.78 mL 93.89 mL 187.79 mL
0.5 mM 3.76 mL 18.78 mL 37.56 mL
1 mM 1.88 mL 9.39 mL 18.78 mL
5 mM 0.38 mL 1.88 mL 3.76 mL

*The above data is based on the productmolecular weight 532.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13045
MECHANISM OF ACTION Inhibitor
M. Wt 532.52
Formula C24H27F3N8O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1034616-18-6
Synonyms NMS1286937, NMS-P937
SMILES CN1CCN(CC1)C2=CC(=C(C=C2)OC(F)(F)F)NC3=NC=C4CCC5=C(C4=N3)N(N=C5C(=O)N)CCO

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