NMS-1286937

Name: NMS-1286937
SKU: A13045
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A13045

PLK 抑制剂

NMS-1286937 是一种口服生物可利用的小分子 Polo-like kinase 1 (PLK1) 抑制剂，具有潜在的抗肿瘤活性。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
5mg	¥385.00	现货
10mg	¥560.00	现货
25mg	¥1,015.00	现货
50mg	¥1,610.00	现货
100mg	¥2,730.00	现货
500mg	¥5,740.00	现货
*10mM 1mL in DMSO**	¥490.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

NMS-1286937 is an orally bioavailable, small-molecule Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic activity.

Targets

Target	Value

产品信息

目录号	A13045
分子式	C24H27F3N8O3
分子量	532.52
CAS号	1034616-18-6
SMILES	CN1CCN(CC1)C2=CC(=C(C=C2)OC(F)(F)F)NC3=NC=C4CCC5=C(C4=N3)N(N=C5C(=O)N)CCO
其他名称	NMS1286937, NMS-P937
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Warmed: 38 mg/mL (71.36 mM)
	Water	Insoluble
	Ethanol	Warmed: 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.78 mL	93.89 mL	187.79 mL
0.5 mM	3.76 mL	18.78 mL	37.56 mL
1 mM	1.88 mL	9.39 mL	18.78 mL
5 mM	0.38 mL	1.88 mL	3.76 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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