NNC 55-0396

Name: NNC 55-0396
SKU: A15188

目录号: A15188

Calcium channel blocker

NNC 55-0396 Chemical Structure

CAS NO. 357400-13-6

NNC 55-0396是Mibefradil衍生物，是一种高度选择性的T型钙通道阻滞剂；分别在INS-1细胞中抑制Cav3.1 T型通道和HVA电流的IC50值为6.8和> 100μM。

库存：现货

规格	价格	数量
10 mg	￥ 1,750.00
50 mg	￥ 4,950.00
100 mg	￥ 8,850.00

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生物活性

NNC 55-0396是Mibefradil衍生物，是一种高度选择性的T型钙通道阻滞剂；分别在INS-1细胞中抑制Cav3.1 T型通道和HVA电流的IC50值为6.8和> 100μM。

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.71 mL	88.56 mL	177.13 mL
0.5 mM	3.54 mL	17.71 mL	35.43 mL
1 mM	1.77 mL	8.86 mL	17.71 mL
5 mM	0.35 mL	1.77 mL	3.54 mL

*The above data is based on the productmolecular weight 564.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A15188
作用机制	Blocker (阻断剂)
M. Wt	564.56
Formula	C30H40Cl2FN3O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	357400-13-6
Synonyms	NNC 55-0396 dihydrochloride
SMILES	CC(C)C1C2=C(CCC1(CCN(C)CCCC3=NC4=CC=CC=C4N3)OC(=O)C5CC5)C=C(C=C2)F.Cl.Cl