NPS-1034

目录号: A15917

c-Met 抑制剂

NPS-1034

NPS-1034 Chemical Structure

CAS NO. 1221713-92-3

NPS-1034是双重Met/Axl抑制剂,IC50分别为48 nM和10.3 nM。

库存: 现货

规格 价格 数量
5 mg
¥ 750.00
10 mg
¥ 1,100.00
25 mg
¥ 2,300.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

NPS-1034是双重Met/Axl抑制剂,IC50分别为48 nM和10.3 nM。
靶点信息
Axl Met
10.3 nM48 nM
In vitro (25°C) DMSO Warmed: 95 mg/mL (172.24 mM)
Water Insoluble
Ethanol 4 mg/mL
In vivo PBS 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.13 mL 90.66 mL 181.31 mL
0.5 mM 3.63 mL 18.13 mL 36.26 mL
1 mM 1.81 mL 9.07 mL 18.13 mL
5 mM 0.36 mL 1.81 mL 3.63 mL

*The above data is based on the productmolecular weight 551.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15917
作用机制 Inhibitor (抑制剂)
M. Wt 551.54
Formula C31H23F2N5O3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1221713-92-3
Synonyms NPS1034, NPS 1034
SMILES O=C(C1=C(C)N(C)N(C2=CC=C(F)C=C2)C1=O)NC3=CC=C(OC4=C5C(NC=C5C6=CC=CC=C6)=NC=C4)C(F)=C3

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