NQDI 1
目录号: A12838
ASK1 抑制剂
NQDI 1 是一种选择性的凋亡信号调节激酶 1(ASK1,MAP3K5)抑制剂(IC50 = 3 μM,Ki = 500 nM)。
Discription | NQDI 1 is a selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50 = 3 μM, Ki = 500 nM). | ||
---|---|---|---|
Targets |
|
目录号 | A12838 |
---|---|
分子式 | C19H13NO4 |
分子量 | 319.31 |
CAS号 | 175026-96-7 |
SMILES | O=C1NC2=CC=CC3=C2C(C4=CC=CC=C4C3=O)=C1C(OCC)=O |
其他名称 | NQDI-1, NQDI1 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 20 mg/mL (62.63 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 5%dmso+40%PEG300+5%tween-80+ddH2O | 0.4 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 31.32 mL | 156.59 mL | 313.18 mL |
0.5 mM | 6.26 mL | 31.32 mL | 62.64 mL |
1 mM | 3.13 mL | 15.66 mL | 31.32 mL |
5 mM | 0.63 mL | 3.13 mL | 6.26 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2