NS-304 (Selexipag)
目录号: A13880
prostacyclin receptor 激动剂
NS-304 是一种选择性前列腺素 IP1 受体激动剂(Ki 值分别为 260 和 2100 nM,针对人类和大鼠的 IP 受体,以及大于 10 μM 对 EP1-4、DP、FP 和 TP 受体)。
Discription | NS-304 is a selective prostacyclin IP1 receptor agonist (Ki values are 260 and 2100 nM and for human and rat IP receptors, and >10 μM for EP1-4, DP, FP, and TP receptors). | ||
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Targets |
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目录号 | A13880 |
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分子式 | C26H32N4O4S |
分子量 | 496.6 |
CAS号 | 475086-01-2 |
SMILES | CC(C)N(CCCCOCC(=O)NS(=O)(=O)C)C1=CN=C(C(=N1)C2=CC=CC=C2)C3=CC=CC=C3 |
其他名称 | Selexipag, ACT-293987 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 84 mg/mL (169.14 mM) | |
Water | Insoluble | ||
Ethanol | 42 mg/mL (84.57 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 20.14 mL | 100.68 mL | 201.37 mL |
0.5 mM | 4.03 mL | 20.14 mL | 40.27 mL |
1 mM | 2.01 mL | 10.07 mL | 20.14 mL |
5 mM | 0.4 mL | 2.01 mL | 4.03 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2