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NSC-23766 HCl

Rac GTPase 抑制剂

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产品目录号: A13975

库存状态:中国现货中国现货

产品名 目录号 价格 数量
NSC-23766 HCl 5mg A13975-5
¥ 450.00
NSC-23766 HCl 10mg A13975-10
¥ 800.00
NSC-23766 HCl 25mg A13975-25
¥ 1,500.00
NSC-23766 HCl 10mM * 1mL in DMSO A13975-10mM-D
¥ 580.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

NSC 23766 is a cell-permeable, reversible inhibitor of Rac1 activation by the Rac-specific GEFs TrioN and Tiam 1 (IC50 = 50 uM).

NSC-23766 HCl

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Chemical Information

目录号 A13975
Mechanism of action Inhibitor
分子量 531
化学分子式 C24H35N7.3HCl
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1177865-17-6
Synonyms NSC 23766, NSC23766
SMILES code CCN(CC)CCCC(C)NC1=NC(=CC(=N1)NC2=CC3=C(C=C2)N=C(C=C3N)C)C.Cl.Cl.Cl
化学名称 N6-[2-[[4-(diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediamine,? trihydrochloride

生物活性

Description
NSC 23766 is a cell-permeable, reversible inhibitor of Rac1 activation by the Rac-specific GEFs TrioN and Tiam 1 (IC50 = 50 uM).
Targets
Rac GTPase (Cell-free assay)
50 μM

溶解性

Solubility (25°C)* In vitro DMSO 100 mg/mL heating (188.33 mM)
Water 100 mg/mL heating (188.33 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.83 mL 94.16 mL 188.32mL
0.5 mM 3.77 mL 18.83 mL 37.66 mL
1 mM 1.88 mL 9.42 mL 18.83 mL
5 mM 0.38 mL 1.88 mL 3.77 mL

*The above data is based on the productmolecular weight 531. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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