NSC 23766

Name: NSC 23766
SKU: A12546
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A12546

Rac1 activation 抑制剂

NSC 23766 是一种选择性的 Rac1-GEF 交互抑制剂。通过 Rac 特异性鸟苷酸交换因子（GEFs）TrioN 和 Tiam1 阻止 Rac1 激活（IC50 约 50 μM），而不影响 Cdc42 或 RhoA 的激活。

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Grouped product items
规格	价格	库存
2mg	¥245.00	现货
5mg	¥420.00	现货
10mg	¥525.00	现货
25mg	¥1,015.00	现货
50mg	¥1,715.00	现货
100mg	¥2,765.00	现货
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Data Sheet

SDS

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生物活性

Discription	NSC 23766 is a selective inhibitor of Rac1-GEF interaction. Prevents Rac1 activation by Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam1 (IC50 ~ 50 μM) without affecting Cdc42 or RhoA activation.

产品信息

目录号	A12546
分子式	C24H35N7
分子量	421.6
CAS号	733767-34-5
SMILES	CCN(CC)CCCC(C)NC1=NC(=CC(=N1)NC2=CC3=C(C=C(N=C3C=C2)C)N)C
其他名称	NSC-23766, NSC23766
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Warmed: 92 mg/mL (173.26 mM)
	Water	Warmed: 92 mg/mL (173.26 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.72 mL	118.6 mL	237.19 mL
0.5 mM	4.74 mL	23.72 mL	47.44 mL
1 mM	2.37 mL	11.86 mL	23.72 mL
5 mM	0.47 mL	2.37 mL	4.74 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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